Sickle Cell Anemia is a common genetic disease that causes long rods in red blood cells, giving them a "sickled" appearance. These cells get stuck in small capillaries of the blood stream leading to oxygen deprivation that causes pain and organ damage. Sickle Cell Anemia is caused by a single point mutation in the hemoglobin gene that results in a faulty protein. In this experiment, your students will investigate the restriction enzyme that discriminates between HbA (normal) and HbS (disease) genes and perform a simulated test on a patient.
All you need: electrophoresis apparatus, power supply, automatic micropipet and tips, balance, microwave or hot plate, visualization system.
Storage: Room Temperature Stable. Storage of Ready-to-Load QuickStrip(tm) samples in the Refrigerator is Recommended.
A note on availability:
This product may not be available directly from PASCO or your local PASCO partner in the following geography: Australia. Please contact us with your interest and we will advise you of availability or refer you to another source.