Antacid Effectiveness -- April, 2002


Teacher Hints:

  1. Except for the probe tip, avoid getting the sensor, interface, or computer wet. Use extra caution with acid solutions near computers!

  2. Hydrochloric acid solution: 100 mL per group will be needed for each antacid brand the group will test. Based on the number of lab groups, dilute enough stock solution ahead of time to have plenty of 0.1 M solution on hand. Remind students of basic cautions to observe when working with acids. Dispose of excess acid properly: remember to neutralize waste HCl with sodium bicarbonate solution or a similar base before flushing down the drain with large amounts of water.

  3. In this experiment students are analyzing the rate of change in pH, not measuring the actual amount of stomach acid neutralized. One possible extension to this experiment would be a titration with a comparable base (i.e., 0.1 M NaOH) to determine the actual volume of acid neutralized.

  4. Based on the active ingredient(s) in the antacid tablets you have chosen to work with, have students write the correct balanced reaction for the neutralization reaction in question. You can find sample reactions for common antacid ingredients at this link: http://www.chem.latech.edu/~deddy/chem104/104Antacid.htm

  5. As time permits for additional trials, challenge students to do a comparative analysis of the effectiveness of different brands of antacids, which can include background research into the active ingredients of popular products. Alternatively, assign different lab groups varying antacid brands to analyze, and compare the final results obtained throughout the class.Remember safety is first.

    SAFETY REMINDERS:

    • Wear protective gear.
    • Follow directions for using the equipment.
    • Handle and dispose of all chemicals and solutions properly.