Alka-Seltzer® Revisited

Investigate the reaction of Alka-Seltzer® tablets with water in an open system. Explain how some mass appears to be "lost."

Alka-Seltzer tablets

Ohaus ScoutTM II Balance (model #SR2020)

Ohaus ScoutTM II Balance
(model #SR2020)

Lab Summary

Students will investigate the reaction of Alka-Seltzer tablets with water in an open system in order to explain how some mass appears to be "lost."

Citric acid (C6H8O7) and sodium bicarbonate (NaHCO3) are the main ingredients in Alka-Seltzer tablets. When the tablets are dropped into water and dissolved, hydrogen ions (H+) and carbonate ions (CO6-2) are freed to collide and react in the solution. The products of the reaction are water and carbon dioxide gas.

Hypothesize: When Alka-Seltzer tablets react with water in an open system, will the total mass of the system increase over time, decrease over time or remain the same? Explain your reasoning.


Published: April 2003

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Other Materials

  • Alka-Seltzer tablets (2)
  • 250-mL plastic beaker
  • 100-mL graduated cylinder
  • weighing paper, double-folded (so that creases in paper cradle the tablets)
  • tap water